The high-end NanoWizard® PURE atomic force microscope from Bruker is a combination of performance and utility. It offers high-resolution imaging and nanomechanical analysis capabilities that can be seamlessly integrated with cutting-edge optical microscopy techniques. It is based on the well-known NanoWizard technology platform.
Features
Performance in its Essence
Renowned Quality
NanoWizard PURE delivers state-of-the-art functionality:
- Unique 3D tip-scanning with capacitive sensor technology
- PeakForce Tapping and QI modes for high-resolution imaging and advanced force control on delicate samples
- The newest V8 software environment offers intuitive operation, automated processes, analysis, and data processing capabilities.
DNA nanostructures were imaged with PeakForce Tapping in a buffer using a Bruker PEAKFORCEHIRS-F-B probe. Scan size: 300 nm × 300 nm; Height range: 2 nm. Image Credit: Bruker BioAFM
NanoWizard PURE is a powerful system that can be seamlessly integrated with optical techniques. Its versatility makes it ideal for the routine and advanced nanomechanical analysis of our samples as diverse as hydrogels, soft tissues, bone, and exoskeletons.
Asst. Prof. Meisam Asgari, University of South Florida, Tampa, USA
Unrivalled Excellence in its Class
With its cutting-edge correlated microscopy techniques, the NanoWizard PURE is the perfect tool for laboratories looking to enhance their research capabilities. It is suitable for novice and seasoned AFM users, using its innovative hardware and software features.
The NanoWizard platform's unmatched modularity offers exceptional versatility. Due to its ease of handling and user-friendliness, it is perfect for imaging facilities with multiple users.
- Discover attractive default configurations for biological and standard applications that offer the best value solutions and capabilities
- Upgrade paths to Bruker BioAFM premium NanoWizard product lines
- Keep apace of technological advances with new modules and features that match your research requirements
PeakForce Tapping image of amyloid fiber Aβ(1-42) on mica in PBS with Bruker FASTSCAN-D probe. Scan size: 650 nm × 240 nm; Height range: 10 nm. Image Credit: Bruker BioAFM
Superior Flexibility
The NanoWizard PURE delivers innovative research capabilities across diverse scientific fields, enabling the exploration of delicate biological samples, including living cells, single molecules, and tissues. It also facilitates the quantification of nanomechanical properties and the study of polymers, soft matter, and advanced materials.
Correlated QI and optical images of live 3T3 fibroblast cells in cell culture medium at 37 °C. Cell nuclei and actin are fluorescently labeled with Hoechst 33342 and CellMask™ Green Actin Tracking, respectively. DirectOverlay semi-transparent superimposition of fluorescence images with optical phase contrast and QI scan. Scan size: 50 μm × 70 μm; Height range: 4 μm (brown); Young’s modulus range: 20 kPa (blue). Image Credit: Dr. Wedepohl, Freie Universität Berlin, Germany
Outstanding Versatility and Range of Accessories
Maximum Functionality
A multitude of modes, add-ons, and accessories offer more capabilities for a wide array of applications. For accurate correlated measurements and improved analysis capabilities, Nano-Wizard PURE can be seamlessly integrated with cutting-edge optical techniques like structured illumination techniques (SIM) and confocal and super-resolution microscopy.
Explore a broad spectrum of features and options, such as:
- Extensive optical integration options, e.g., DirectOverlay 2, DirectTiling, and accessories for operation on inverted optical microscopes
- ExperimentPlanner
- Force spectroscopy ramp designer
- Latest ease-of-use features
- MFM, EFM
- Nanolithography and Nanomanipulation
- PeakForce QNM and QI advanced options for quantitative nanomechanical analysis
Stained peripheral nerve tissue from Mus musculus. DirectTiling of optical images superimposed with QI scan using DirectOverlay. Scan size: 100 μm × 100 μm. Height range: 50 nm. Image Credit: Dr. Macgregor-Fairlie, Charité Berlin, Germany, & R. Doherty and C. Griffiths, University of Southampton, UK.
Enhanced Adaptability
The NanoWizard PURE can be tailored to meet the unique demands of individual users, specific samples, and diverse applications. It is particularly well-suited for interdisciplinary research facilities and collaborative scientific environments. Expand your research potential with a variety of customizable options, such as:
- Kelvin Probe Microscopy
- Conductive AFM
- Piezoresponse Force Microscopy
- Cytosurge FluidFM® technology
- Contact Resonance AFM
- Scanning Tunneling Microscopy
- Scanning Thermal AFM
- Electrochemistry and SECM with temperature control and full optical access
- Micropipette capabilities
Piezoresponse Force Microscopy (PFM) of a ferroelectric polymer thin film (P(VDF-TrFE)) on a gold back electrode on silicon. A sequence of voltage pulses was generated from a bitmap template (black = +20 V, white = 0 V) to write the logo into the piezoelectric polarization of the sample. Scan size: 45 μm × 10 μm; Vertical PFM-amplitude range: 150 pm.
Magnetic Force Microscopy (MFM) scan of different magnetic domain patterns on a hard disc close to an intersector gap. Scan size: 8.5 µm × 5.8 µm. MFM phase range: 2 deg
The new easy-to-use cantilever holder with a hinge clip option is biocompatible and multicompartment compatible. Image Credit: Bruker BioAFM
NanoWizard PURE Bio (right) and Standard (left) configurations at attractive rates. Image Credit: Bruker BioAFM