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PDS Biotechnology Initiates Vaccination Trial with PDS0101 Nanotechnology Vector for Cervical Intraepithelial Neoplasia

PDS Biotechnology Corp., a clinical-stage biotechnology company focused on the development of novel immunotherapy treatments for cancer and other chronic diseases, as well as novel preventive vaccines, today announced that the first patient has been successfully vaccinated with PDS0101 in a Phase 1 clinical trial in patients with cervical intraepithelial neoplasia.

12 Feb 2014

Sorrento to Present Study Results of Nanoparticle Form of Paclitaxel in Metastatic Pancreatic Cancer

Sorrento Therapeutics, Inc. (Sorrento), a late-stage clinical oncology company developing new treatments for cancer and associated pain, today announced that it will present results of preclinical and Phase II clinical studies of Cynviloq™ in patients with metastatic pancreatic cancer at the Beaujon International Conference: Cutting Edge in Liver and Pancreatic Tumors in Paris, France on February 13, 2014.

12 Feb 2014

‘Self-Assembled Multivalent' Approach to Nanomedicine

A University of York scientist's experience in seeing his partner in hospital recovering from a double lung transplant prompted him to design and synthesise new chemical agents that could revolutionise post-operative patient care.

12 Feb 2014

Rapamycin-Loaded Nanoparticles Used to Treat Muscular Dystrophy in Mice

Researchers at Washington University School of Medicine in St. Louis have demonstrated a new approach to treating muscular dystrophy. Mice with a form of this muscle-weakening disease showed improved strength and heart function when treated with nanoparticles loaded with rapamycin, an immunosuppressive drug recently found to improve recycling of cellular waste.

12 Feb 2014

Novel Method to Print Living Cells onto Any Surface

With a nod to 3rd century Chinese woodblock printing and children's rubber stamp toys, researchers in Houston have developed a way to print living cells onto any surface, in virtually any shape. Unlike recent, similar work using inkjet printing approaches, almost all cells survive the process, scientists report in this week's Proceedings of the National Academy of Sciences.

12 Feb 2014

MIT Chemical Engineers Design Nanoparticles Capable of Silencing Disease-Causing Genes

Inspired by tiny particles that carry cholesterol through the body, MIT chemical engineers have designed nanoparticles that can deliver snippets of genetic material that turn off disease-causing genes.

From Massachusetts Institute of Technology 11 Feb 2014

Nanotech Firm, Genisphere Granted US Patent for Whole Transcriptome Next Generation Sequencing

Genisphere LLC reported today it has been granted a US patent for a novel strand-specific library preparation method for next generation sequencing based on its proven RNA amplification technology. The new patented process enables amplification and library preparation from clinically relevant RNA samples, adapts easily to a variety of sequencing instruments and systems, and reduces the time required for sample preparation by eliminating labor intensive steps.

11 Feb 2014