Liposomes are an existing drug delivery vehicle, but they are detected by the immune system. Researchers from the universities of Basel and Fribourg have demonstrated that specially synthesized liposomes do not produce any reaction in human and porcine sera, as well as pigs.
With support from the state of Florida, Mayo Clinic’s Florida campus has opened a state-of-the-art laboratory for nanotechnology research, an emerging field of science that studies and applies materials that are the size of an atom.
Researchers at Karolinska Institutet have developed a nanoparticle technology that can be used to stabilise membrane proteins so that their structure can be studied in a lipid environment. The method, described in Nature Methods, makes it possible to access drug targets that previously could not be investigated and therefore potentially allows for the development of novel drugs, therapeutic antibodies and vaccines.
A scientific innovator, whose achievements range from developing diagnostic biochips to creating nanoscale cancer-fighting “smart bullets” that deliver treatments to tumor cells, has been recruited to the OHSU Knight Cancer Institute to lead the first large-scale early cancer detection program of its kind.
Cancer is a group of diseases characterized by the uncontrolled growth and spread of abnormal cells. It is a leading cause of death and the burden is expected to grow worldwide due to the growth and aging of the population, mainly in less developed countries, in which about 82% of the world's population resides.
Recent research on graphene oxide may enhance our ability to fight infections acquired from hospitals and other places. Researchers from the Università Cattolica del Sacro Cuore in Rome are analyzing graphene oxide in the hope of successfully developing bacteria-killing medical devices and catheters in the near future. Bacteria can be killed by coating all surgical equipment with the carbon-based compounsd. This will result in faster recovery times, reducing the number of post-operative infections, and reducing the requirement for antibiotics.
Biopsies are a gold standard for definitively diagnosing diseases like cancer. Usually, doctors can only take two-dimensional snapshots of the tissue, and they're limited in their ability to measure the protein levels that might better explain a diagnosis.
Researchers at The Hebrew University of Jerusalem have developed a nanotechnology-based delivery system containing a protective cellular pathway inducer that activates the body's natural defense against free radicals efficiently, a development that could control a variety of skin pathologies and disorders.
Osteosarcoma is a cancer present in the bones of adolescents and children. Considered an aggressive cancer, Osteosarcoma has only a 15 per cent, five-year survival rate when detected in an advanced metastatic stage. Every year in the US there are about 800 new cases of osteosarcoma with no suitable treatment.
Keywords such as nano-, personalized-, or targeted medicine sound like bright future. What most people do not know, is that nanomedicines can cause severe undesired effects for actually being too big! Those modern medicines easily achieve the size of viruses which the body potentially recognizes as foreign starting to defend itself against - a sometimes severe immune response unfolds.
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