Litesizer Series of Particle Size Analyzers

The Litesizer DLS series classifies nanoparticles and microparticles at the press of a button. These dynamic light scattering devices allow users to identify particles in dispersion as well as peptides or macromolecules in solution across a wide concentration range, reducing sample preparation time.

• Litesizer DLS 100
  • Particle size measurements from the nanometer to the micrometer range
  • DLS backscatter detection ensures a broad concentration range
  • Automatic measurement modes
  • Continuous transmittance measurement
• Litesizer DLS 500
  • Particle characterization from the nanometer to the micrometer range
  • Particle size measurements using dynamic light scattering at three separate measurement angles
  • Determination of zeta potential using patented cmPALS
  • Molecular mass and refractive index measurements
• Litesizer DLS 700
  • Particle characterization from the nanometer to the micrometer range
  • High resolution of different size populations via multi-angle particle sizing (MAPS)
  • Determine the concentration of up to three distinct size classes within one sample

Key Features

Benefit from the Perfect Angle Choice – Whatever the Sample

Image Credit: Anton Paar GmbH

• Ensure great resolution of diverse size populations using multi-angle particle sizing (MAPS)
• To optimize parameter settings, select one of three detection angles (side, rear, or forward scattering)
• Manually choose the best angle for the dynamic light scattering device or utilize automatic angle selection.
• Benefit from the flexible backscattering angle, which is suitable for turbid samples and eliminates numerous scattering events to provide optimal data quality

Rely on the cmPALS Technique for Zeta Potential Measurements

Image Credit: Anton Paar GmbH

• Measure zeta potential using electrophoretic light scattering using the Litesizer DLS 700 and DLS 500
• The proprietary cmPALS technology (European Patent 2 735 870) allows for very sensitive readings at low sample concentrations (as low as 0.1 mg/mL)
• cmPALS provides quicker measuring times and less sample deterioration
• The zeta potential cuvettes include a distinctive Ω-shaped capillary, allowing for extremely reproducible results

Stay Flexible with the Particle Concentration Measurement Mode

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• With the Litesizer DLS 700, users can perform calibration-free particle concentration measurements of up to three distinct size populations inside one sample.
• This mode based on single-angle DLS or multi-angle particle sizing (MAPS) ensures the applicability to monodisperse and polydisperse samples across a large concentration range.

Get Continuous Transmittance Measurements for Sample Monitoring

Image Credit: Anton Paar GmbH

• Obtain continuous transmittance measurements for sample monitoring
• Use automated optimization of measurement parameters (e.g., measurement angle, focus position, duration)
• Access data on the commencement of sedimentation or aggregation within a series of measurement

Determine Refractive Index with the Same Instrument

Image Credit: Anton Paar GmbH

• Measure the refractive index of the solvent at the precise wavelength and temperature of DLS or ELS measurements (European Patent 3 023 770) using Litesizer DLS 700 and Litesizer DLS 500
• Under all experimental circumstances, ensure that particle size and zeta potential results are as accurate as possible.
• Use Litesizer DLS 700 and DLS 500 to measure refractive index to within ±0.5% accuracy.

Control the Measurements with Just a Few Clicks

Image Credit: Anton Paar GmbH

• Manage data using Kalliope, the user-friendly particle sizing program
• The innovative one-page process allows users to see the input parameters, measurement signals, and outcomes at a glance
• Quickly evaluate measurement results with established standard reports and organized result overviews
• Explore the data using an analysis function, Excel export, and customized report templates
• Comply with 21 CFR Part 11

Technical Specifications

Source: Anton Paar GmbH