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Quantum Dot-Based Method for Analysis of DNA Methylation

One of the earliest events that changes a normal cell into a malignant one is known as deoxyribonucleic acid (DNA) hypermethylation, a biochemical alteration that inactivates critical tumor-suppressor genes. A team of in...

21 Jul 2009

Nanotechnology Revolutionizing Therapeutic Drug Discovery

Understanding the structure of proteins is a vital first step in developing new drugs, but to date, researchers have had difficulty studying the large number of proteins that are normally embedded in the cell membrane, a...

21 Jul 2009

First Implantable Diagnostic Device for Cancer Monitoring

Surgical removal of a tissue sample is now the standard for diagnosing cancer. Such procedures, known as biopsies, are accurate but offer only a snapshot of the tumor at a single moment in time. Monitoring a tumor fo...

21 Jul 2009

Targeted Iron Oxide Nanoparticles Could Serve as Novel Imaging Agents for Early Detection of Breast Tumors

Current methods of detecting breast cancer suffer from low sensitivity, limited spatial resolution, or the need to use complicated and expensive radioisotope-based technologies. A new report from investigators at the Emo...

21 Jul 2009

Products Designed to Meet the Demands of Molecular Diagnostics Market

SAFC Supply Solutions, a business segment of SAFC, a member of the Sigma-Aldrich Group (Nasdaq: SIAL), today announced the launch of a diverse product offer designed to meet the demands of the burgeoning molecular diagno...

21 Jul 2009

Using Subatomic Particles to Treat Cancer

Proton therapy -- which uses beams of the subatomic particles to treat cancer -- is a hot topic at this year's American Association of Physicists in Medicine (AAPM) meeting, which takes place from July 26 - 30 in Ana...

20 Jul 2009

Single-Molecule Experiments Show How Mechanical Strength in Muscles is Anchored in Titin-Telethonin Complex

A research collaboration between Munich-based biophysicists and a structural biologist in Hamburg is helping to explain why our muscles, and those of other animals, don't simply fall apart under stress. Their finding...

20 Jul 2009

Three Purdue Research Park-Based Firms Named Companies to Watch

En'Urga, Kylin Therapeutics and Passageways, three Purdue Research Park-based firms, were named by the Indiana Economic Development Corp. in its second annual list of 50 Companies to Watch.

20 Jul 2009

New Biosensor Detects Extremely Low Bacteria Concentrations Quickly, Easily, and Reliably

As reported in the journal Angewandte Chemie, their new method is based on electrochemical measurements by means of carbon nanotubes equipped with aptamers as bacteria-specific binding sites. If bacteria bind to the aptamers, the researchers detect a change in electrical voltage.

20 Jul 2009

Microscopic Technique to Pursue Individual Nanoparticles as They Make Their Way into Target Cells

In future therapies, synthetic nanoparticles may well be able to ferry medicines and even genes to targets inside the body. These nanovehicles can now be directly tested and optimized using a highly sensitive microscopic...

20 Jul 2009