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Rubbery Properties of RNA Nanoparticles Provide High Tumor Targeting Efficiency

Rubbery Properties of RNA Nanoparticles Provide High Tumor Targeting Efficiency

A new study by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute shows that RNA nanoparticles have elastic and rubbery properties that help explain why these particles target tumors so efficiently and why they possess lower toxicity in animal studies.

15 Sep 2020

New Nanoparticle Antitumor Vaccines Control Melanoma Growth in Preclinical Models

New Nanoparticle Antitumor Vaccines Control Melanoma Growth in Preclinical Models

At the Wistar Institute, researchers merged synthetic DNA technology with their expertise in protein engineering to successfully create nanoparticle antitumor vaccines that stimulated strong CD8 T cell immunity and regulated melanoma growth in preclinical models.

11 Sep 2020

New Nano System Enhances the Effectiveness of Melanoma Treatment

New Nano System Enhances the Effectiveness of Melanoma Treatment

Researchers at Tel Aviv University, led by Prof. Ronit Satchi-Fainaro of TAU's Department of Physiology and Pharmacology at the Sackler School of Medicine, have developed an innovative nanotechnological drug delivery system that significantly enhances the effectiveness of treatment for the aggressive skin cancer melanoma.

9 Sep 2020

New Nanomachine Helps Explore Peptide-Loading Complex Involved in Immune System

New Nanomachine Helps Explore Peptide-Loading Complex Involved in Immune System

An extraordinary nanomachine performed a small but significant step towards an effective immune reaction. Simulations are used by scientists to figure out its operation.

31 Aug 2020

DNA Nanoswitches Show Potential for Rapid Detection of Emerging Viruses

DNA Nanoswitches Show Potential for Rapid Detection of Emerging Viruses

Programmable DNA nanoswitches that bind to viral RNA in human body fluids may provide an inexpensive platform to rapidly detect a wide variety of emerging viruses, including SARS-CoV-2, according to a new study.

24 Aug 2020

Engineered Lipid-Based Nanoparticles Show Promise for Treating Genetic Disorders

Engineered Lipid-Based Nanoparticles Show Promise for Treating Genetic Disorders

Inserting genetic material into the body to treat diseases caused by gene mutations can work, scientists say - but getting those materials to the right place safely is tricky.

24 Aug 2020

New Technique can Identify and Quantify Viral RNA in Living Cells

New Technique can Identify and Quantify Viral RNA in Living Cells

Many viruses, including HIV and influenza A, mutate so quickly that identifying effective vaccines or treatments is like trying to hit a moving target.

20 Aug 2020

Nanopore Technique Shows Potential as Quick-and-Easy Tool for Mutation Detection

Nanopore Technique Shows Potential as Quick-and-Easy Tool for Mutation Detection

In recent years, a non-invasive biopsy method called liquid biopsy has shown promise as a potential alternative to tissue biopsy, currently the gold standard in cancer detection and diagnosis.

19 Aug 2020

Combination of Nanotechnology and Genetic Engineering for Regulating Cancer Stemness

Combination of Nanotechnology and Genetic Engineering for Regulating Cancer Stemness

The development of chemotherapeutic agents with selective anti-cancer activities is increasingly unattractive due to the emergence of resistance, poor targeting of cancer tissues, and subsequent metastasis.

18 Aug 2020

Tunnelling Nanotubes Regulate Blood Supply to Keep Vision Intact

Tunnelling Nanotubes Regulate Blood Supply to Keep Vision Intact

A new mechanism of blood redistribution that is essential for the proper functioning of the adult retina has just been discovered in vivo by researchers at the University of Montreal Hospital Research Centre.

13 Aug 2020

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