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Researchers Reveal Chiral Structure of Gold Nanoclusters

The theoretical structure was confirmed via comparison to experimental results obtained by X-ray diffraction from powder samples of the pure cluster material.

The theoretical work was done in collaboration with researchers at Kansas State University and the experimental part at Hokkaido University. The team is supported by the Academy of Finland and the CSC – the IT Center for Science.

The synthesis of organothiolate-protected gold clusters of 1 to 3 nm in size has been well known since the mid-1990s, but the detailed atomic structure of the most stable clusters remained a mystery until very recently. In 2007, the structure of the first cluster that contained 102 gold atoms was resolved at Stanford University using single-crystal X-ray crystallography. The cluster now resolved has exactly 38 gold atoms and 24 organothiolate molecules covering its surface and it is just about one nanometer (nanometer = one millionth of a millimeter) in size. The shape of the particle is prolate (cigar-like), and 15 out if its 38 gold atoms reside on the protective surface layer chemically bound with the thiolate molecules. The gold-thiolate layer has a chiral structure, which is responsible for the observed chiral properties. The chiral structure has two structural forms (enantiomers), the so-called right-handed and left-handed forms, in a way comparable to a twist in a DNA molecule or to a twist in the staircase structure of a block of flats.

Chirality is a very common structural property of molecules in nature.  The chiral nature of gold clusters influences the way they respond to circularly polarised light. This effect was first reported in experiments by Professor Robert L. Whetten's team at Georgia Institute of Technology (Atlanta, USA) exactly ten years ago. “We observed that particularly the 38-atom cluster (for which no structural information was available) is very sensitive for the polarisation of light, and the now-resolved structure finally explains our observations,” comments Professor Whetten. In the future, chiral gold nanoclusters could be used as bio-compatible, enantioselective sensors, drug carriers or catalysts.

Professor Häkkinen's team at the University of Jyväskylä has played a world-leading role in theoretical structural determination and characterisation of thiolate-protected gold nanoclusters over the last few years. The team has collaborated with researchers at Stanford University, Georgia Institute of Technology, Kansas State University, the University of North Carolina, Chalmers University of Technology and Hokkaido University.

Source: http://www.aka.fi/

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