Malaria parasites invade human red blood cells, they then disrupt them and infect others. Researchers at the University of Basel and the Swiss Tropical and Public Health Institute have now developed so-called nanomimics of host cell membranes that trick the parasites. This could lead to novel treatment and vaccination strategies in the fight against malaria and other infectious diseases. Their research results have been published in the scientific journal ACS Nano.
A research team led by physicists at the University of Wisconsin-Milwaukee (UWM) has proven a method that makes it possible to find the atomic structure of proteins in action by producing “snapshots” of them with unprecedented spatial and temporal resolution.
Cells are restless. They move during embryogenesis, tissue repair, regeneration, chemotaxis. Even in disease, tumor metastasis, cells get around. To do this, they have to keep reorganizing their cytoskeleton, removing pieces from one end of a microtubule and adding them to the front, like a railroad with a limited supply of tracks. The EB family of proteins helps regulate this process and can act as a scaffold for other proteins involved in pushing the microtubule chain forward.
Human biology is a massive collection of chemical reactions, from the intricate signaling network that powers our brain activity to the body’s immune response to viruses and the way our eyes adjust to sunlight.
Professor Stephan Irle and Yoshio Nishimoto at the Institute of Transformative Bio-Molecules (ITbM) of Nagoya University and Dr. Dmitri Fedorov of the National Institute of Advanced Industrial Science and Technology (AIST, Tsukuba) have developed a novel ultrafast quantum chemical method enabling rapid simulations of molecules containing more than a million atoms without detrimental loss in accuracy.
The synthetic biology market is rapidly evolving, with various technological advancements that have resulted in a paradigm shift within the market. This has resulted in advanced production of synthetic genes and chassis to develop synthetic organisms from scratch.
A new technology that reveals cellular gene transcription in greater detail has been developed by Dr. Daniel Kaufmann of the University of Montreal Hospital Research Centre (CRCHUM) and the research team he directed.
MIT biological engineers have created a new computer model that allows them to design the most complex three-dimensional DNA shapes ever produced, including rings, bowls, and geometric structures such as icosahedrons that resemble viral particles.
A research team from Kiel University (CAU) and Goethe University Frankfurt have jointly created a synthetic surface on which the adhesion of E. coli bacteria can be controlled. The layer, which is only approximately four nanometres thick, imitates the saccharide coating (glycocalyx) of cells onto which the bacteria adhere such as during an infection.
Sienna Labs announced today that the U.S. Patent and Trademark Office issued U.S. Patent No. 8,895,071 covering, among other aspects, methods of using the company's plasmonic nanoparticle platform for localizing thermal damage to sebaceous glands and hair, a key mechanism for their investigational acne treatment and hair removal indications.
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