Sometimes simplicity is best. Two Northwestern University researchers have discovered a remarkably easy way to make nanofluidic devices: using paper and scissors. And they can cut a device into any shape and size they want, adding to the method's versatility.
Tumor cells circulating in a patient’s bloodstream can yield a great deal of information on how a tumor is responding to treatment and what drugs might be more effective against it. But first, these rare cells have to be captured and isolated from the many other cells found in a blood sample.
The disease atherosclerosis involves the build up of fatty tissue within arterial walls, creating unstable structures known as plaques. These plaques grow until they burst, rupturing the wall and causing the formation of a blood clot within the artery. These clots also grow until they block blood flow; in the case of the coronary artery, this can cause a heart attack.
A new power-free microfluidic chip developed by researchers at the RIKEN Advanced Science Institute (ASI) enables detection of microRNA from extremely small sample volume in only 20 minutes. By drastically reducing the time and quantity of sample required for detection, the chip lays the groundwork for early-stage point-of-care diagnosis of diseases such as cancer and Alzheimer's.
It may soon be possible to test a person for cancer with just a drop of their blood and a small machine. As part of a European research project, scientists have developed a device for detecting the HSP70 protein, which i...
Fluidigm Corporation today introduced four new integrated fluidic circuits (IFCs) designed to meet the challenges associated with production genomics. These new offerings are expected to make substantial contributions to laboratories performing high sample throughput digital PCR, genotyping, and targeted panel testing.
In an advance toward analyzing blood and urine instantly at a patient's bedside instead of waiting for results from a central laboratory, scientists are reporting development of a new micropump capable of producing pressures almost 500 times higher than the pressure in a car tire.
Using something called “inertial microfluidics,” University of Cincinnati researchers are able to continuously and selectively collect rare cells, such as circulating tumor cells, based on their size vs. other biomarkers. This could reduce analysis time and increase selectivity while reducing reliance on antibody-based testing in clinical tests.
Scientists have developed a small microfluidic device that can be used for performing hundreds of biochemical analyses. It has the capability of measuring 768 biomolecular interactions.
The National Human Genome Research Institute (NHGRI), which is part of the National Institutes of Health (NIH), has announced grants of nearly $19 million for developing technologies that could drastically bring down DNA sequencing costs. Many of the projects are utilizing nanotechnology to achieve this motive.
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