Waters’s Centers of Innovation Program recognition was awarded to Dr Joseph Dalluge who heads the Mass Spectrometry Laboratory of University of Minnesota. Dr Joseph Dalluge was honored for his research in the development of diagnostic marker assays to determine cystic fibrosis and other such diseases.
Joseph Dalluge is one of the 13 researchers that the Waters’ Centers of Innovation Program has recognized. The program supports the efforts of the researchers who use mass spectrometry and liquid chromatography to achieve breakthrough in the field of food safety, sports medicine, environmental protection and life sciences research.
The Dalluge mass spectrometry laboratory is a part of the university’s department of chemistry. Dr Dalluge’s research uses advanced mass spectrometry / liquid chromatography instrumentation for biomarker discovery, metabolite profiling, assay development and detailing the chemical characterization of various biological systems.
The Vice President – Strategic Innovation and the Program Director of the innovation program, Tim Riley stated that Dr Dalluge and his laboratory will receive the support of the Centers of Innovation Program. Riley praised Dr Dalluge’s efforts in bringing ideas to life and his attempt at understanding the chemical basis of diseases, adaptation and molecular signaling.
Dr Dalluge explained the power of combining mass spectrometry with Ultra Performance Liquid Chromatography (UPLC) technology by stating that it was possible to compare dissimilar biological systems and determine the differences at the molecular level to determine the characteristics of a non-disease state and a disease state. This can lead to determining the differences between a young cell and an aging cell and cells exposed to inflammation agents against those not exposed. The professor explained that by combining UPLC and an MS platform, it is possible to study complex biological systems.
The Waters ACQUITY UPLC / SYNAPT G2 platform and ACQUITY UPLC / TQD play a vital role in the research for assay development, biomarker discovery and metabolite profiling.